Successful pregnancy and delivery in a woman with gray platelet syndrome.

[B] Electron microscope image (x 10,000) of a normal platelet showing the presence of dense (black arrow) and α-granules (green arrow) Transmission of gray platelet syndrome is autosomal-dominant in some cases but recessive in others, suggesting heterogeneity in the origin of the defect [2]. Thrombocytopenia in pregnancy is not rare. It is observed in 6% to 15% of pregnant women at the end of pregnancy and is usually moderate. Gestational thrombocytopenia is the most common cause of thrombocytopenia during pregnancy, occurring in approximately 7% of women. It is thought to be caused by estrogen-mediated suppression of megakaryocytopoiesis [3]. The potential effect of pregnancy on the platelet count in gray platelet syndrome has not been described and the outcome of such pregnancies is unknown. In this report, we describe the course of a pregnancy and delivery in a patient with gray platelet syndrome.